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Year : 2022  |  Volume : 29  |  Issue : 3  |  Page : 206-213

Day and night blood pressure variability among older persons in South-Western Nigeria

1 Department of Medicine, University of Ibadan, Ibadan, Nigeria
2 Chief Tony Anenih Geriatric Centre, University College Hospital, Ibadan, Nigeria
3 Department of Public Health, Osun State University, Osogbo, Nigeria
4 Department of Pharmacology and Therapeutic, College of Medicine, University of Ibadan, Ibadan, Nigeria
5 Department of Anatomy, University of Ibadan, Ibadan, Nigeria
6 Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia

Correspondence Address:
Lawrence Adekunle Adebusoye
Chief Tony Anenih Geriatric Centre, University College Hospital, Ibadan
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/npmj.npmj_24_22

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Background: Hypertension is the largest contributor to the global burden of disease. Emerging risk factors for cardiovascular disease include blood pressure variability (BPV), but evidence on BPV is lacking among older Nigerians. We reported BPV in a cohort of older persons at the University College Hospital (UCH), Ibadan. Methods: We conducted a retrospective cohort study of respondents aged >50 years within the Ibadan Ambulatory Blood Pressure Registry at the UCH, Ibadan, Nigeria. Socio-demographic characteristics, lifestyle habits and anthropometric measurements were obtained. Results: Among 639 respondents, 332 (52.0%) were female. The blood pressure (BP) variables were strongly associated with age. Compared with younger age groups, mean diastolic BP (DBP) was less at an older age, whereas mean pulse pressure was greater. During the wake-up and sleep periods, mean DBP and mean arterial BP were less with each increasing age category, whereas mean pulse pressure was larger with each increasing age category. BP dipping, systolic, diastolic and mean arterial BP decreased with age. Overall, timed BPV increased significantly with increasing age. The prevalence of white-coat hypertension was greater among older participants than younger participants. Most respondents in the 50–59 years' age group were non-dippers (55.8%), whereas 33.7% of older respondents were reverse-dippers. Conclusion: Older persons experienced a greater abnormal circadian blood variation and greater BPV than younger people. In Nigeria, follow-up data are needed to determine the prognostic significance of these data in this population.

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