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Year : 2013 | Volume
: 20
| Issue : 1 | Page : 9-13 |
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Bacterial isolates from cerebrospinal fluid of children with suspected acute meningitis in a Nigerian Tertiary Hospital
SI Nwadioha1, EOP Nwokedi1, I Onwuezube2, JO Egesie3, E Kashibu4
1 Department of Medical Microbiology, College of Health Sciences, Benue State University, Makurdi, Nigeria 2 Department of Medical Microbiology, Univ. of Uyo Teaching Hospital, Uyo, Akwa Ibom state, Nigeria 3 Department of Haematology, Jos University Teaching Hospital, Jos, Nigeria 4 Department of Microbiology, Aminu Kano Teaching Hospital, Kano, Nigeria
Correspondence Address:
S I Nwadioha Department of Medical Microbiology, College of Health Sciences, Benue State University, Makurdi Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |

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Aims and Objectives: To determine the common aetiolog of acute bacterial meningitis in children and their antibiotic susceptibility pattern.
Materials and Methods: A retrospective study with a review of cerebrospinal fluid culture reports of paediatric patients aged 0-15 years, suspected of acute meningitis in the Medical Microbiology Department of Aminu Kano Teaching Hospital, Kano, Nigeria from October 2006 to October 2009 from October 2006 to October 2009.
Results: A positive culture bacterial isolation rate of 3.3% (n=50/1500) with prevalence of Streptococcus pneumoniae (24%), Neisseria meningitidis(22%), Escherichia coli(16%), Haemophilus influenzae (14%), Group B streptococci(8%) and Enterococci(8%) which were susceptible to ceftriaxone(96%), cefotaxime(95%) and ciprofloxacin(93%) across the bacterial isolates. Neonates were 55% (n=6.8/12.4) most at risk.
Conclusion: Neonates are the most at risk of acute bacterial meningitis. In the absence of antibiotic susceptibility report, ceftriaxone should be considered as a first choice reliable antibiotic for empirical treatment of meningitis in children, in this environment. |
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